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What is Special About Our Technology

Why Breathability Matters

Traditional shake flasks often suffer from poor gas exchange, leading to oxygen limitation and COâ‚‚ buildup — a major bottleneck in early-stage process development. Aero-Yield, a disruptive innovation, solves this by maximizing surface-driven diffusion while maintaining flask integrity and sterility.

Increased Oxygen Transfer

Conventional flasks rely on limited headspace exchange, restricting oxygen availability during high-demand growth phases. Aero-Yield flasks feature breathable walls that dramatically enhance Oâ‚‚ transfer across the entire surface, supporting robust aerobic metabolism and accelerating cell expansion.

Sensor-Ready

Integrating inline sensors into traditional flasks is often bulky, leaky, or infeasible. Aero-Yield’s smart-ready design supports seamless integration of NON-INVASIVE sensors —enabling real-time monitoring of DCOâ‚‚, DO, and other parameters without compromising sterility or flask performance.

Sterile & Scalable

Designed for seamless scalability, they are available in multiple volumes—all while maintaining consistent gas exchange efficiency.

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"“Look deep into nature, and then you will understand everything better.”"

Albert Einstein

Cultures and Sensors

For a detailed history of shake flask cultures and sensors, free download of Dr. Rao’s book “Sensor Techknowledge: Sensors for Process Development: A Practical Guide” is available at:

Peer-Reviewed Paper

Peer-reviewed journal publication, presenting the unique capabilities of breathable technology, titled "Reinventing shake flask fermentation: The breathable flask" is available at:

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